Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications
نویسندگان
چکیده
منابع مشابه
Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications.
Recently, a new type of electrokinetic concentration devices has been developed in a microfluidic chip format, which allows efficient trapping and concentration of biomolecules by utilizing ion concentration polarization near nanofluidic structures. These devices have drawn much attention not only due to their potential application in biomolecule sensing, but also due to the rich scientific con...
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A perm-selective nanochannel could initiate concentration polarization near the nanochannel, significantly decreasing (increasing) the ion concentration in the anodic (cathodic) end of the nanochannel. Such strong concentration polarization can be induced even at moderate buffer concentrations because of local ion depletion (therefore thicker local Debye layer) near the nanochannel. In addition...
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ژورنال
عنوان ژورنال: Chemical Society Reviews
سال: 2010
ISSN: 0306-0012,1460-4744
DOI: 10.1039/b822556g